Article Library
The Gut Microbiome and the Influence of Non-Antibiotic Medication
In a previous article, I discussed the profound effects that antibiotics have on the gut microbiome. Other medications greatly influence the microbiota, as well. One of the most widely-used medications is the proton pump inhibitor (PPI). In fact, in 2013 esomeprazole (Nexium, also known as “the purple pill”) was the second largest revenue-making drug in the United States.
Why should antibiotic stewardship be important to the patient?
According to the Centers for Disease Control and Prevention (CDC), antibiotics have advanced medical care by treating previously known fatal conditions and extending life. Yet, the inappropriate use of these medications can contribute to antibiotic resistance, adverse risks (like C. diff), longer hospital stays, higher medical costs, and negatively affect population health [1]. In fact, antibiotic resistance can be a factor to medical harm, causing 2 million infections and 23,000 deaths annually [2]. Judicious use of antibiotics is therefore important, yet the CDC relates that 30% of prescribing in both inpatient and outpatient settings are not necessary [1, 2].
Prescription use among senior adults
Taking medications seems like a very natural responsibility as part of aging. In fact, most seniors take a prescription drug. Adults over 65 are the largest age group to take medications, due to the amount of health concerns that people acquire [1].